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Nanoscale Research Letters will move under the Discover Journal Series and rebrand to Discover Nano starting 1 January 2023. Papers submitted to Nanoscale Research Letters prior to 1 January will still be considered in Discover Nano.

Analysis of Actin and Focal Adhesion Organisation in U2OS Cells on Polymer Nanostructures

In this work, we explore how U2OS cells are affected by arrays of polymer nanopillars fabricated on flat glass surfaces. We focus on describing changes to the organisation of the actin cytoskeleton and in the location, number and shape of focal adhesions. From our findings we identify that the cells can be categorised into different regimes based on their spreading and adhesion behaviour on nanopillars. A quantitative analysis suggests that cells seeded on dense nanopillar arrays are suspended on top of the pillars with focal adhesions forming closer to the cell periphery compared to flat surfaces or sparse pillar arrays. This change is analogous to similar responses for cells seeded on soft substrates.

Article collections open for submissions

NRL regularly publishes thematic collections of articles focusing on a specific topic, guest edited by experts in the field. We currently have a number of collections open for submissions.

Be sure to click the "collections" tab in the Articles box below to view the collections that have already been published!


  1. Authors: Abolfazl Akbarzadeh, Rogaie Rezaei-Sadabady, Soodabeh Davaran, Sang Woo Joo, Nosratollah Zarghami, Younes Hanifehpour, Mohammad Samiei, Mohammad Kouhi and Kazem Nejati-Koshki


Two-Dimensional Materials: Science and Technology
Edited by Yu Jia, Xiaoyu Han, Hao Xu and Fang Zhao
Started publishing: 09 May 2020 


Smart Nanomaterials
Edited by Anna Baldycheva
Started publishing: 21 May 2019


Applications of Atomic Layer Deposition
Edited by: Gaoshan Huang, Wen-Jun Liu and Xinwei Wang
Started publishing: 24 December 2018

Metasurfaces and Metamaterials
Edited by: Jiang Wu, Peng Yu, Yongjun Huang and Zhiming Wang
Started publishing: 29 November 2018

Metal halide perovskite materials and devices
Edited by: Shibin Li, Wei Zhang
Started publishing: 20 July 2018


3rd International Conference on ALD Applications & 2016 China ALD conference
Collection published: 13 January 2017


Nanotechnology and Nanomaterials (NANO-2014)
Edited by: Dr. Olena Fesenko, Prof Leonid Yatsenko
Collection published: 27 February 2015


2nd International Conference on ALD Applications & 3rd China ALD conference
Edited by: Prof Yongfeng Mei, Prof Shi-Jin Ding
Collection published: 23 December 2014

2014 International Symposium on Next-Generation Electronics (ISNE 2014)
Edited by: Prof Jer-Chyi Wang, Dr peikuen wei, Prof. Chao Sung Lai
Collection published: 25 August 2014

Porous Semiconductors - Science and Technology PSST2014
Edited by: Prof Leigh Canham, Nobuyoshi Koshida, Prof Thierry Djenizian, Michael J. Sailor, Prof Andres Cantarero
Collection published: 25 June 2014

First International Conference on Nanomaterials and Nanotechnology - Algeria
Edited by: Prof Nacer Badi, Dr Alex Ignatiev, Prof Mohamed Guerioune
Collection published: 5 April 2014

2014 China-Korea Symposium on Low Dimensional Electronic and Photonic Materials and Devices
Edited by: Prof Xia Guo, Prof Hyeonsik Cheong
Collection published: 27 February 2014

Nanotechnology and nanomaterials (NANO-2013)
Edited by: Dr Olivier Pluchery, Dr. Olena Fesenko, Prof Leonid Yatsenko
Collection published: 20 February 2014

Novel gain materials and devices based on III-V-N/Bi compounds
Collection published: 13 January 2014


Low dimensional electric and photonic materials and devices
Edited by: Prof Chang Liu, Prof Hyeonsik Cheong
Collection published: 2 December 2013

EMN Meeting
Edited by: Prof Zhiming Wang, Prof Jiang Wu
Collection published: 4 June 2013

13th Trends in NanoTechnology International Conference
Edited by: Antonio Correia, Prof Xavier Cartoixa, Prof Juan Jose Saenz
Collection published: 1 May 2013

The Fifth International Symposium on Atomically Controlled Fabrication Technology
Edited by: Prof Yukio Takahashi, Yuji Kuwahara
Collection published: 27 March 2013

Risk assessment of manufactured nanomaterials
Edited by: Prof Enzo Lombi, Prof Nicolas Voelcker
Collection published: 1 March 2013

1st International Conference on ALD Applications & 2nd China ALD conference
Edited by: Prof Yongfeng Mei, Prof Shi-Jin Ding
Collection published: 15 February 2013


EMRS-E SiGe 2012
Edited by: Dr Artur Podhorodecki, Dr Grzegorz Zatryb
Collection published: 21 December 2012

International Conference on Superlattices, Nanostructures, and Nanodevices (ICSNN 2012)
Edited by: Prof Oliver G. Schmidt, Prof Manfred Helm, Dr Rinaldo Trotta
Collection published: 29 August 2012

Porous Semiconductors - Science and Technology 2012
Edited by: Prof Andres Cantarero
Collection published: 1 July 2012

12th Trends in NanoTechnology International Conference (TNT2011)
Collection published: 14 May 2012

Nano and Giga Challenges 2011
Edited by: Dr Predrag Krstic, Prof Dario Narducci, Prof Yurii Lozovik, Dr Anatoli Korkin
Collection published: 1 March 2012

Edited by: Prof Jin-Hyo Boo
Collection published: 1 January 2012

INEC 2011
Collection published: 1 January 2012


Nano Component 2011
Collection published: 29 July 2011

11th Trends in NanoTechnology International Conference (TNT2010)
Collection published: 7 April 2011

Micro&Nano2010: Special Symposium on Nanomaterials for sensing and energy harvesting devices
Edited by: Prof Androula Nassiopoulou
Collection published: 22 March 2011

Symposium E : Nanoscaled Si, Ge based materials
Edited by: Dr Artur Podhorodecki
Collection published: 31 January 2011

Advanced Materials Nanocharacterization
Collection published: 31 January 2011

Edited by: Prof Liqiu Wang, Prof Oronzio Manca, Prof Yogesh Jaluria, Prof Stephen Choi
Collection published: 25 January 2011

International Conference on Superlattices, Nanostructures and Nanodevices (ICSNN 2010)
Collection published: 12 January 2011

Online First articles in Volume 6 (2011). These articles were published as Online First on SpringerLink in 2010. They should be cited with a 2011 publication year
Nanoscale Research Letters
Collection published: 1 January 2011


8th International Workshop on Epitaxial Semiconductors on Patterned Substrates and Novel Index Surfaces
Collection published: 1 August 2010

Nanoscale science and technology for electronics, photonics and renewable energy applications: Selected papers from NGC2009 & CSTC2009 conference
Collection published: 6 January 2010

Indexing services

Nanoscale Research Letters is indexed in the following sources:

  • Academic OneFile
  • Agricola
  • Astrophysics Data System (ADS)
  • CAS
  • Chemical and Earth Sciences
  • ChemWeb
  • Current Abstracts
  • Current Contents
  • DOAJ
  • Ei Compendex
  • EmBiology
  • Gale
  • Journal Citation Reports/Science Edition
  • Materials Science Citation Index
  • OCLC
  • PubMed
  • PubMed Central
  • Science Citation Index Expanded
  • Scimago Journal & Country Rank
  • Scopus
  • Summon by Serial Solutions
  • VINITI - Russian Academy of Science

Announcing the launch of In Review

Nanoscale Research Letters, in partnership with Research Square, is now offering In Review. Authors choosing this free optional service will be able to:

  • Share their work with fellow researchers to read, comment on, and cite even before publication
  • Showcase their work to funders and others with a citable DOI while it is still under review
  • Track their manuscript - including seeing when reviewers are invited, and when reports are received

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