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  • Nano Express
  • Open Access

Computer-aided design of nano-filter construction using DNA self-assembly

Nanoscale Research Letters20062:24

  • Received: 1 August 2006
  • Accepted: 29 September 2006
  • Published:


Computer-aided design plays a fundamental role in both top-down and bottom-up nano-system fabrication. This paper presents a bottom-up nano-filter patterning process based on DNA self-assembly. In this study we designed a new method to construct fully designed nano-filters with the pores between 5 nm and 9 nm in diameter. Our calculations illustrated that by constructing such a nano-filter we would be able to separate many molecules.


  • Computer-aided design
  • Nano-filter
  • DNA
  • Self-assembly


(See supplementary material 1)



This work was supported by Shiraz University. The authors would like to thank Dr. Mohammad Hossein Sheikhi, Prof. Afsaneh Safavi, Prof. Mahmood Barati-Khajooie, Dr. Ali Amiri and Mr. Babak Saffari for their helpful comments on the manuscript.

Authors’ Affiliations

Department of Biology, College of Sciences, Shiraz University, Shiraz, Iran


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© to the authors 2006