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Table 1 Represents the zone of inhibition (in terms of diameter square) for free antibiotics and antibiotics conjugated with Gnps in three bacterial strains

From: In Vitro Structural and Functional Evaluation of Gold Nanoparticles Conjugated Antibiotics

Name of the bacterial strain

Name of antibiotics

Inhibitory zone in sq. diameter (cm2)

% Change in inhibitory sq. diameter

Free antibiotics

Gnps-conjugated antibiotics

E. coli DH5 α (Gram −Ve)

Ampicillin

3.085 ± 0.146

3.569 ± 0.160

+15.688

Streptomycin

2.189 ± 0.057

2.453 ± 0.102

+12.060

Kanamycin

3.371 ± 0.164

4.545 ± 0.223

+34.826

M. luteus(Gram +Ve)

Ampicillin

8.740 ± 0.201

10.493 ± 0.354

+20.057

Streptomycin

0.818 ± 0.091

1.712 ± 0.241

+109.291

Kanamycin

2.507 ± 0.118

2.960 ± 0.149

+18.069

S. aureus(Gram +Ve)

Ampicillin

14.839 ± 0.321

16.659 ± 0.678

+12.265

Kanamycin

1.588 ± 0.098

2.132 ± 0.150

+34.257

  1. The concentrations of free as well as Gnps conjugated antibiotics are 50 μg/ml for ampicillin, 10 μg/ml for streptomycin and 50 μg/ml for kanamycin. The data is the average of three experiments ± SD. Percentage change in each case is calculated and mentioned above

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