Scheme 1
From: Single-component Polymer Nanocapsules for Drug Delivery Application
Schematic representation of the preparation of single-component macromolecular capsules by using solid core and mesoporous shell (SC/MS) silica particles as templates. The process involves the infiltration of polyelectrolyte or polymer-drug conjugates into mesoporous shells of SC/MS particles (step 1), followed by crosslinking of the infiltrated polymer chains (step 2) and subsequent removal of the SC/MS silica template (step 3), leading to thick-walled polyelectrolyte or drug-conjugated polymer nanocapsules