Figure 1
Hematoxylin and eosin staining of mouse lung tissue. (ae) Fluronic F-68-treated group acts as the solvent control. (bf) Early response (3 days) of the mouse lung tissue to a single dose of 0.5 mg of SWNT. (cdgh) Two weeks response of the mouse lung tissue to a single dose of 0.5 mg of SWNT. (fg) SWNT-loaded foamy-like macrophages in the alveolae; (h) multifocal macrophage-containing granuloma around the sites of SWNT aggregates. (ad) Original magnification ×100, bar = 100 um; (eh) ×400. The black arrows shown in panels b and c indicate the SWNT-loaded foamy-like macrophages. Reprinted with permission from [23]. Copyright (2004) American Chemical Society