Figure 3

Immune responses induced by the functionalized-MWNT library. Library members were assayed for MWNT-induced NO release (a and b) in macrophages at either 50 μg/mL or 200 μg/mL. The basal level of NO release by LPS (100 ng/mL) is marked on panels a and b. The f-MWNT library-induced NO release in the presence of LPS (100 ng/mL) is shown as vertical bars. The precursor, Carboxylated MWNT, generated high response as shown at the lower right corner. The plots are presented in library format showing all amine and acylator building blocks used in synthesizing this MWNT library