Skip to main content

Table 1 Organic macromolecules and their advantages of functionalized iron oxide NPs

From: Magnetic Iron Oxide Nanoparticles: Synthesis and Surface Functionalization Strategies

Polymers Advantages References
Natural Polymers Dextran Enables optimum polar interactions with iron oxide surfaces, improves the blood circulation time, stability, and biocompatibility [6467]
Starch Improves the biocompatibility, good for MRI, and drug target delivery [68, 69]
Gelatin Used as a gelling agent, hydrophilic emulsifier, biocompatible [7072]
Chitosan Non-toxic, alkaline, hydrophilic, widely used as non-viral gene delivery system, biocompatible, and hydrophilic [7375]
Synthetic Polymers Poly(ethyleneglycol) (PEG) Enhance the hydrophilicity and water-solublility, improves the biocompatibility, blood circulation times [7678]
Poly(vinyl alcohol) (PVA) Prevents agglomeration, giving rise to monodispersibility [7981]
Poly(lactide acid) (PLA) Improves the biocompatibility, biodegradability, and low toxicity in human body [82, 83]
Alginate Improves the stability and biocompatibility [84, 85]
Polymethylmethacrylate (PMMA) Generally used as thermosensitive drug delivery and cell separation [8688]
Polyacrylic acid (PAA) Improves stability and biocompatibility as well as bioconjugation [89, 90]