Table 3 IC50 of MCF-7 cells after 24-, 48-, 72-h incubation with docetaxel formulated in the Taxotere®, 5% DMAB-modified PLGA nanoparticles (ANP), unmodified PLGA-TPGS nanoparticles (BNP) and 5% DMAB-modified PLGA-TPGS nanoparticles (CNP)
From: Oral Delivery of DMAB-Modified Docetaxel-Loaded PLGA-TPGS Nanoparticles for Cancer Chemotherapy
Incubation time (h) | IC50(μg/ml) | |||
---|---|---|---|---|
ANP | BNP | CNP | Taxotere® | |
24 | 1.144 | 1.300 | 0.121 | 2.610 |
48 | 0.926 | 0.590 | 0.088 | 1.640 |
72 | 0.272 | 0.204 | 0.054 | 0.911 |