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Table 1 The effect of the different type of polymers on characteristic of NPs.

From: Novel docetaxel-loaded nanoparticles based on poly(lactide-co-caprolactone) and poly(lactide-co-glycolide-co-caprolactone) for prostate cancer treatment: formulation, characterization, and cytotoxicity studies

Polymeric NPs

Size (nm)

PDI

EE (%)

YP (%)

PLA

146.3 ± 23.5

0.198 ± 0.03

37.8 ± 3.0

51.9 ± 1.4

PLGA

106.7 ± 13.5

0.108 ± 0.04

35.2 ± 2.6

68.2 ± 2.7

PLA-PCL

194.8 ± 31.2

0.308 ± 0.08

19.7 ± 1.4

36.8 ± 1.6

PLGA-PCL

114.8 ± 15.4

0.258 ± 0.07

47.2 ± 3.8

83.9 ± 3.3

  1. Data are shown as mean ± S.D., obtained from three formulations. PDI, polydispersity index; EE, encapsulation efficiency; YP, yield of production

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