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Table 2 The effect of molar ratio of Solutol HS15 to mPEG-PLA on properties of micelles.

From: Preparation and evaluation of novel mixed micelles as nanocarriers for intravenous delivery of propofol

Molar ratio of Solutol HS15 to mPEG-PLA 0:10 1:9 5:5 7:3
Drug-free micelles size (nm) 88.1 ± 4.1 83.3 ± 3.5 80.2 ± 3.6 78.3 ± 5.1
PDI 0.16 ± 0.03 0.17 ± 0.04 0.19 ± 0.07 0.16 ± 0.06
Drug-loaded micelles size (nm) 119.9 ± 5.5 117.1 ± 6.1 101.0 ± 3.8 94.4 ± 6.4
PDI 0.17 ± 0.11 0.19 ± 0.04 0.12 ± 0.09 0.18 ± 0.08
LC (%) 21.1 ± 3.2 26.5 ± 1.5* 32.4 ± 1.3** 36.0 ± 2.4***
  1. * p > 0.05 versus plain micelles
  2. ** p < 0.01 versus plain micelles
  3. *** p > 0.05 versus mixed micelles with 5:5 molar ratio of Solutol HS15 to mPEG-PLA