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Table 2 SC dose exposure comparison (nanosuspension versus regular suspension)

From: Investigation of utilization of nanosuspension formulation to enhance exposure of 1,3-dicyclohexylurea in rats: Preparation for PK/PD study via subcutaneous route of nanosuspension drug delivery

Dose (mg/kg) C max(μM) ± STDEV C min24hr(μM) ± STDEV AUC0-t(h*μM) ± STDEV t1/2(h) ± STDEV
30 mg/kg (nanosuspension) 0.82 ± 0.03 0.20 ± 0.02 11.0 ± 0.5 10.2 ± 0.8
30 mg/kg (regular suspension) 0.13 ± 0.02 0.06 ± 0.02 2.0 ± 0.8 34.4 ± 21.4