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Figure 6 | Nanoscale Research Letters

Figure 6

From: CdTe quantum dots with daunorubicin induce apoptosis of multidrug-resistant human hepatoma HepG2/ADM cells: in vitro and in vivo evaluation

Figure 6

Signal pathway analysis. (A) Western blotting analysis of P-gp in HepG2/ADM cells. HepG2/ADM cells without treatment were used as control (lane 1). Lysates were prepared from the cells treated 4 μM Cdte QDs with 4 × 10-6 mol/L DNR (lane 2). (B) The control cells without any treatment (1). The images were taken from cells treated with 4 μM Cdte QDs with 4 × 10-6 mol/L DNR for 72 h (2). Bar, 20 μm. (C) Western blotting analysis of cytochrome c released in HepG2/ADM cells: group 1, control group (lane 1); group 2, 4 × 10-6 mol/L DNR (lane 2); group 3, 4 μM Cdte QDs (lane 3); and group 4, 4 μM Cdte QDs with 4 × 10-6 mol/L DNR (lane 4). The following antibodies were used: anti-cleaved caspase-9, anti-cleaved caspase-3, and anti-PARP antibody. GAPDH was served as a loading control.

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