Figure 6
From: Dendrimer-entrapped gold nanoparticles as potential CT contrast agents for blood pool imaging
Planar projection images after intravenous injection of {(Au0) 51.2 -G5.NHAc} DENPs or iohexol. Rows I, II, and III contain images obtained after injection of the Au DENPs, iohexol, and PBS, respectively. In each row, image (a) is the pre-contrast image, (b) was taken 5 min after contrast injection, (c) at the 20-min, and (d) at 60 min after contrast injection. The following structures could be clearly distinguished 5 min after Au DENP injection (I-b): the heart (arrow), renal vein (oval arrow), main portal vein (arrow head), and branches of the portal vein (diamond arrow). At 20 min (I-c), the renal vein (oval arrow), main portal vein (arrow head), and branches of the portal vein (diamond arrow) remained distinct. Sixty minutes after Au DENP injection (I-d), the vascular system could no longer be visualized, but the urinary system, including the ureter (open arrow) and the urinary bladder (open arrow head), could be seen distinctly. After iohexol injection (II), the vascular system of the experimental mice could not be imaged. The urinary system began to be imaged 5 min after iohexol injection (II-b), and after 60 min (II-c), only the urinary bladder was defined.