Account

Table 1 Independent variables and their corresponding variables of NP preparation for RCCD

From: Preparation and optimization of matrix metalloproteinase-1-loaded poly(lactide-co-glycolide-co-caprolactone) nanoparticles with rotatable central composite design and response surface methodology

Variables	Levels
Variables	−1.682	−1	0	+1	+1.682
X₁ (min)	2	4	7	10	12
X₂ (krpm)	2	2.8	4	5.2	6
X ₃	0.1	0.18	0.3	0.42	0.5

RCCD, rotatable central composite design; X₁, duration time of homogenization; X₂, agitation speed of homogenization; X₃, volume ratio of organic solvent phase to external aqueous phase.

Back to article page