Figure 5
From: Control of growth and inflammatory response of macrophages and foam cells with nanotopography
Changes in cytokine and chemokine gene expression profiles. (a) Macrophages and (b) foam cells were cultured on nanodot arrays of different sizes for 72 h, and qPCR was conducted to evaluate gene expression of TNF-α, IL-6, CCL-3, IL-10, and CCL-2. Gene expression profiles for genes were involved in circulatory repair. (c) Macrophages and (d) foam cells were cultured on nanodot arrays of different sizes for 72 h, and qPCR was conducted to evaluate gene expression of PAI-1, VEGF and PECAM.