Table 1 Some of the infectious diseases and QDs used to distinguish them
From: Quantum dots: synthesis, bioapplications, and toxicity
Authors | Type of infectious diseases | In vitro / in vivo | Type of modified QDs |
|---|---|---|---|
Tripp et al. [89] | RSV | In vitro/in vivo | Antibody anti-F protein conjugated to QDs(CdTe) |
Agrawal et al. [90] | Individual molecules of genes, proteins, and virus particles | In vivo | QD-antibody color-coded NP probes and two-color co-localization imaging |
Bentzen et al. [91] | RSV | In vivo | Streptavidin-coated QDs conjugated to antibody anti-F and antibody anti-G |
Dwarakanath et al. [92] | S. typhimurium | In vivo | Antibody-QD and DNA aptamer-QD |
E. coli | |||
B. subtilis spores | |||
Goldman et al. [93] | Choleratoxin, ricin, shinga-like toxin1 and staphylococcal enterotoxin B | In vitro | Antibody-QD (CdSe/Zns) |
Zhao et al. [94] | Food-borne pathogenic E. coli O157:H7, S. typhimurium and S. flexneri | QDanti-S. flexneri antibody,anti-E. coli antibody, anti-S. typhimurium antibody | |
Hahn et al. [95] | Single cells of E.coli O157:H7 | Streptavidin-coated QDs conjugated to antibody | |
Mukhopadhyay et al. [96] | Detect E. coli at levels as low as 104 bacteria/ml of sample | Mannose-conjugated QDs | |
Edgar et al. [97] | Mycobacterium | In vivo | Streptavidin-coated QDs conjugated to phage |
B. anthracis | |||
Zhu et al. [98] | C. parvum | QD-conjugated antibodies | |
G. lamblia | |||
Klostranec et al. [99] | Biomarkers of the most globally prevalent blood-borne infectious diseases (i.e., hepatitis B, hepatitis C, and HIV) with low sample volume | QD-antibody | |
Gazouli et al. [100] | Mycobacterium genus | In vivo | Specific DNA sequences combining QDs with magnetic beads [101, 102] |
Hahn et al. [95] | Individual pathogenic E. coli O157:H7 in phosphate buffer saline solution | Streptavidin-coated Qdots labeled by antibody selectively targeted pathogenic E. coli O157:H7 | |
Su and Li [51] | E. coli O157 | In vivo | Streptavidin-coated QDs conjugated to anti-E. coli O157 antibody |
Yang and Li [52] | E. coli O157∶H7 | In vivo | QDs with different sizes conjugated to anti-E. coli O157 and anti-Salmonella antibodies |
S. typhimurium | |||
The bead-cell complexes reacted with QD-antibody conjugates to form bead-cell-QD complexes |