Table 1 Characterization of sorafenib-incorporated nanoparticles
Polymer/drug (mg/mg) | Drug contents (%, w/w) | Loading efficiency (%, w/w) | Particle size (nm) | Zeta potential (mV) | |
|---|---|---|---|---|---|
Theoretical | Experimental | ||||
40:0 | - | - | - | 46 ± 1.12 | -36.4 ± 3.1 |
40:2 | 4.76 | 1.23 | 25.84 | 63 ± 0.58 | -35.5 ± 2.2 |
40:5 | 11.11 | 4.36 | 39.24 | 133 ± 0.58 | -36.0 ± 1.1 |
40:7 | 14.89 | 5.26 | 35.33 | 181 ± 1.15 | -35.8 ± 0.9 |