Table 7 Ames test results of mice (revertant colonies)
From: Systematic safety evaluation on photoluminescent carbon dots
Dose (mg/plate) | Strains | ||||
|---|---|---|---|---|---|
TA97 | TA98 | TA100 | TA102 | ||
0.1 | -S9 | 129.3 ± 11.4 | 32.3 ± 6.7 | 134.7 ± 20.0 | 290.0 ± 33.4 |
+S9 | 128.7 ± 25.0 | 38.0 ± 6.9 | 138.3 ± 13.2 | 294.0 ± 28.0 | |
0.05 | -S9 | 128.7 ± 15.1 | 33.0 ± 7.8 | 132.0 ± 16.0 | 279.3 ± 22.0 |
+S9 | 139.3 ± 8.3 | 35.7 ± 5.5 | 132.0 ± 18.3 | 295.7 ± 14.4 | |
0.025 | -S9 | 131.3 ± 9.0 | 33.0 ± 7.2 | 128.7 ± 12.2 | 280.0 ± 13.1 |
+S9 | 142.0 ± 11.1 | 40.0 ± 5.3 | 151.0 ± 13.5 | 302.3 ± 19.3 | |
0.0125 | -S9 | 118.0 ± 13.5 | 33.3 ± 6.4 | 127.7 ± 19.7 | 279.3 ± 28.4 |
+S9 | 121.3 ± 11.0 | 34.0 ± 6.5 | 134.7 ± 16.2 | 284.3 ± 17.6 | |
Negative control | -S9 | 135.3 ± 14.7 | 31.0 ± 4.6 | 136.7 ± 24.4 | 294.0 ± 27.5 |
+S9 | 131.0 ± 26.5 | 41.0 ± 4.0 | 130.7 ± 18.0 | 288.7 ± 20.4 | |
Positive solvent group | -S9 | 130.3 ± 14.6 | 33.7 ± 4.2 | - | 284.0 ± 20.3 |
+S9 | 130.7 ± 12.1 | 34.7 ± 6.1 | 137.3 ± 13.3 | 295.3 ± 21.4 | |
Positive control | -S9 | 803.3 ± 165.0 | 893.3 ± 220.3 | 640.0 ± 91.7 | 946.7 ± 122.2 |
+S9 | 780.0 ± 177.8 | 1,160.0 ± 183.3 | 746.7 ± 140.5 | 1,000.0 ± 208.8 | |