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Table 2 Morphological and biomechanical parameters of differentiated cells detected by AFM

From: The roles of integrin β1 in phenotypic maintenance and dedifferentiation in chondroid cells differentiated from human adipose-derived stem cells

Group

Surface average roughness (R a) (nm)

Root mean square roughness (R q) (nm)

Adhesive force (pN)

Young’s modulus (kPa)

ADS

46.700 ± 4.495b

72.450 ± 7.246b

182.326 ± 18.229a

1.597 ± 0.110b

3DD

71.155 ± 7.096a,b

106.448 ± 12.070a,b

200.254 ± 17.138a

2.059 ± 0.179a,b

6DD

72.407 ± 7.621a,b

106.721 ± 13.489a,b

261.688 ± 19.416a,b

2.314 ± 0.207a,b

9DD

85.044 ± 7.170a,b

104.311 ± 11.333a,b

301.049 ± 22.776a,b

2.405 ± 0.213a

12DD

220.847 ± 21.308a,b

300.940 ± 29.248a,b

410.440 ± 28.638a,b

2.711 ± 0.236a

15DD

169.844 ± 16.589a,b

218.186 ± 17.884 a,b

369.682 ± 26.958a,b

2.996 ± 0.233a

18DD

154.426 ± 12.985a,b

180.992 ± 18.232a,b

306.807 ± 23.506a,b

3.090 ± 0.234a

21DD

116.913 ± 12.361a,b

151.729 ± 13.340a,b

181.895 ± 18.648b

3.518 ± 0.381a,b

NC

303.205 ± 29.475a

362.011 ± 35.296a

639.197 ± 47.678a

2.742 ± 0.200a

  1. aCompared with ADS, P < 0.05; bCompared with NC, P < 0.05.

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