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Figure 4 | Nanoscale Research Letters

Figure 4

From: Surface modification of TPGS-b-(PCL-ran-PGA) nanoparticles with polyethyleneimine as a co-delivery system of TRAIL and endostatin for cervical cancer gene therapy

Figure 4

Effects of PEI modification, binding of pDNA with TPGS- b -(PCL- ran -PGA)/PEI nanoparticles, and FESEM image of HNP. (A) The effects of PEI modification on particle size. (B) The effects of PEI modification on surface charge. (C) The binding of pDNA with TPGS-b-(PCL-ran-PGA)/PEI nanoparticles determined by agarose gel electrophoresis. A series of different weight ratios (w/w) of pDNA to TPGS-b-(PCL-ran-PGA)/PEI nanoparticles was loaded on the agarose gel (a, pDNA/NPs = 1:0; b, pDNA/NPs = 1:4; c, pDNA/NPs = 1:10; d, pDNA/NPs = 1:20; e, pDNA/NPs = 1:20; f, pDNA/NPs = 1:20). (D) FESEM image of TRAIL- and endostatin-loaded TPGS-b-(PCL-ran-PGA)/PEI nanoparticles (HNP).

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