Table 3 Gemcitabine contents (μg/g) in different organs of SD rats
From: Gemcitabine-loaded albumin nanospheres (GEM-ANPs) inhibit PANC-1 cells in vitro and in vivo
Organ | 110-nm GEM-ANPs | 406-nm GEM-ANPs | Gemcitabine |
---|---|---|---|
Heart | 104.9 ± 11.1 | 113.3 ± 18.9 | 117.1 ± 15.9 |
Liver | 2.7 ± 2.5* | 43.6 ± 13.4* | 8.0 ± 7.2 |
Spleen | 2.8 ± 1.9* | 35.3 ± 7.8* | 16.9 ± 5.1 |
Pancreas | 101.6 ± 13.8 | 155.6 ± 11.8* | 112.6 ± 5.8 |
Lung | 8.0 ± 3.7 | 8.3 ± 3.6 | 13.9 ± 7.3 |
Muscle | 92.8 ± 15.1 | 81.6 ± 11.3 | 84.9 ± 5.4 |
Kidney | 105.8 ± 15.6 | 92.1 ± 12.9 | 99.7 ± 7.7 |