From: Gemcitabine-loaded albumin nanospheres (GEM-ANPs) inhibit PANC-1 cells in vitro and in vivo
Group | Tumor volume (mm3) | Volume change, ΔV(mm3) | Inhibitory rate of volumea(%) | Tumor weightb(g) | Inhibitory rate of weightc(%) | |
---|---|---|---|---|---|---|
5 days | 35 days | |||||
110-nm GEM-ANPs | 144.9 ± 12.2 | 187.3 ± 32.4 | 42.4 | 75.1 | 0.175 | 39.9 |
406-nm GEM-ANPs | 148.2 ± 10.4 | 31.0 ± 16.1 | −117.2 | 168.8* | 0.090* | 69.1* |
Gemcitabine | 149.64 ± 20.35 | 132.80 ± 28.2 | −16.8 | 109.9 | 0.166 | 43.0 |
ANPs | 147.6 ± 22.7 | 250.6 ± 27.2 | 103.0 | 39.6 | 0.245 | 15.81 |
Control | 149.4 ± 18.2 | 319.9 ± 30.3 | 170.5 | 0.0 | 0.291 | 0.0 |