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Table 3 Effects of carbon dots on T lymphocyte subsets in spleen of BALB/c mice

From: Carbon dots: a safe nanoscale substance for the immunologic system of mice

Groups	CD4+ (%)	CD8+ (%)	CD4+/CD8+
Saline	25.97 ± 0.65	9.94 ± 1.01	2.63 ± 0.21
Carbon dots
2 mg/kg	24.95 ± 0.20	12.54 ± 0.26**↑	1.99 ± 0.04**↓
10 mg/kg	24.31 ± 0.41**↓	11.00 ± 0.14	2.21 ± 0.05**↓
50 mg/kg	26.51 ± 0.44	12.75 ± 0.12**↑	2.08 ± 0.04**↓

The effects were recorded 1 day after administration. Data are presented as mean ± standard deviations, n = 5. **P < 0.01 compared with the saline group (control). Significant difference was calculated by one-way ANOVA using SPSS19.0.

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