Table 1 Sequence alignment between Kv1.3, Na v Ab, and Nav1.8
From: Designing a C84 fullerene as a specific voltage-gated sodium channel blocker
Sequence alignment | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Kv1.3 | V | V | T | M | T | T | V | G | Y | G | D | Ma |
NavAb | F | Q | V | M | T | L | Eb | S | W | S | Ma | G |
Nav1.8 I | F | R | L | M | T | Q | Db | S | W | E | R | La |
Nav1.8 II | F | R | I | L | C | G | Eb | W | I | E | N | Ma |
Nav1.8 III | L | Q | V | A | T | F | Kb | G | W | M | D | Ia |
Nav1.8 IV | F | Q | I | T | T | S | Ab | G | W | D | G | La |