Figure 3

VLP H1 and VLP H2 inhibit breast cancer cell migration and invasion. (A) VLP H1 and VLP H2 inhibited the invasion of MDA-MB-231 cells. Data are presented as mean ± SEM, n = 5. Ctrl vs VLP H1; Ctrl vs VLP H2, p < 0.01. (B) Statistic results of net distance of the cells that treated with PBS, 10 μM VLP H1 or VLP H2. (C) Statistic results of directionality of the cells that treated with PBS, 10 μM VLP H1 or VLP H2. (D) Statistic results of total distance of the cells that treated with PBS, 10 μM VLP H1 or VLP H2. (E) Statistic results of velocity of the cells that treated with PBS, 10 μM VLP H1 or VLP H2. The data are expressed as mean ± SEM of more than 60 cells from at least three independent experiments. Single asterisk (*) denotes P < 0.05 and double asterisk (**) P < 0.01 compared to control. (F) Migration tracks of 10 MDA-MB-231 cells that treated with PBS, 10 μM VLP H1 or VLP H2.