Table 2 Mascot result of significantly altered spots
From: A comparative study of lung toxicity in rats induced by three types of nanomaterials
Spot | Protein name | Score | Change | Function |
|---|---|---|---|---|
1 | Macrophage-capping protein | 97 | ↑ | Immunity |
17 | IgE-dependent histamine-releasing factor | 81 | ↑ | Immunity |
12 | Heat shock 27 kDa protein 1 | 104 | ↑ | Immunity |
2 | Inward rectifier potassium channel protein IRK 3 | 72 | ↓ | Ion channel |
4 | Potassium voltage-gated channel subfamily A member 3 | 91 | ↓ | Ion channel |
13 | Glutathione peroxides 1 | 109 | ↓ | Oxidation stress |
10 | Glutathione S-transferase alpha 5 | 63 | ↑ | Oxidation stress |
8 | Glutathione transferase | 88 | ↑ | Oxidation stress |
11 | Ubiquinol-cytochrome-c reductase | 79 | ↓ | Metabolism |
3 | ATP synthase subunit alpha | 83 | ↓ | Metabolism |
7 | ADP/ATP transport protein | 72 | ↓ | Metabolism |
9 | Ca2+-transporting ATPase | 94 | ↓ | Metabolism |
5 | Phosophatidylethanolamine binding protein (TOF-TOF) | 177 | ↑ | Signal transduction |
14 | Annexin A11 (TOF-TOF) | 89 | ↑ | Signal transduction |
15 | GTP-binding protein Rab40c | 90 | ↑ | Signal transduction |
16 | Protein-tyrosine-phosphatase isoenzyme AcP1 | 117 | ↑ | Signal transduction |
6 | Transgelin 2 (Sm22 alpha) (TOF-TOF) | 121 | ↑ | Cytoskleton |