Table 1 Effects of thiolated chitosan modification on size, encapsulation efficiency, and zeta potential
From: Thiolated chitosan-modified PLA-PCL-TPGS nanoparticles for oral chemotherapy of lung cancer
Group | Polymer | Size (nm) | PDI | Zeta potential (mV) | Drug content (%) | EE (%) | Thiolated chitosan modification |
|---|---|---|---|---|---|---|---|
CNP | PCL | 203.56 ± 4.35 | 0.335 | −19.63 ± 4.10 | 8.69 | 86.55 | 5% |
UNP | PLA-PCL-TPGS | 198.46 ± 2.49 | 0.246 | −18.29 ± 3.25 | 9.89 | 98.79 | None |
TNP | PLA-PCL-TPGS | 206.15 ± 3.66 | 0.286 | 24.66 ± 4.19 | 9.79 | 97.56 | 5% |
DNP | PLA-PCL-TPGS | 219.33 ± 4.25 | 0.317 | 26.18 ± 5.02 | 9.88 | 98.55 | 20% |