Figure 5
Effect of ZnO NPs on mitochondrial transmembrane potential in cultured primary astrocytes. The cells were treated with 4, 8, or 12 μg/ml of ZnO NPs or 12 μg/ml of ZnO NPs plus 5 mM NAC for 6 h, respectively. Astrocytes were pretreated for 1 h with 5 mM of NAC before 6 h of co-exposure with ZnO NPs (12 μg/ml). Data are presented as the mean ± SD of three representative experiments. *p < 0.05, **p < 0.01, ***p < 0.001 vs. control. #p < 0.05 vs. ZnO NPs (12 μg/ml).