Table 1 Exposure (mean value) of paclitaxel in plasma, tumor, liver, and spleen following intravenous administration
Tissue AUC0-8 (μM × h) | Formulation | |
---|---|---|
Cremophor EL:ethanol | Nanosuspension | |
Plasma | 74.7 | 2.1 |
Tumor | 52.1 | 17.5 |
Liver | 269.1 | 1,701.1 |
Spleen | 85.2 | 147.5 |