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Table 1 Characterizations of nanoparticulate non-viral vectors in gene delivery

From: A sight on the current nanoparticle-based gene delivery vectors

Non-viral vectors Transferring efficiency Preparation Cellular toxicity Applications References
Inorganic nanoparticles Low Easy Frequently toxic In vitro [18, 48, 56]
Polymer-based nanoparticles Low Easy Low toxicity In vitro [25, 29, 31]
Lipid-based nanoparticles Low Difficult Toxic (at high dose) In vitro [20]
Hybrid nanoparticles High Easy Low toxicity In vitro/In vivo [25, 73]