Table 1 Characterizations of nanoparticulate non-viral vectors in gene delivery
From: A sight on the current nanoparticle-based gene delivery vectors
Non-viral vectors | Transferring efficiency | Preparation | Cellular toxicity | Applications | References |
|---|---|---|---|---|---|
Inorganic nanoparticles | Low | Easy | Frequently toxic | In vitro | |
Polymer-based nanoparticles | Low | Easy | Low toxicity | In vitro | |
Lipid-based nanoparticles | Low | Difficult | Toxic (at high dose) | In vitro | [20] |
Hybrid nanoparticles | High | Easy | Low toxicity | In vitro/In vivo |