Figure 9
From: Toxicity evaluation of zinc aluminium levodopa nanocomposite via oral route in repeated dose study
Micrograms showing neuronal nucleus from the substantia nigra. TEM ultra-structural micrographs of the rat substantia nigra (n = 3) showing the nucleus of a neuron after treatment with (A) ZALH, (B) ZALL, (C) ZAH, (D) ZAL and (E) VC. Arrow pointing to the intact round-shaped nuclei with a densely peripheral nuclear chromatin condensation (opaque nuclei membrane) and mitochondria (M), with well-outlined cristae and intact opaque membrane in the control group. Similar nucleic and mitochondrial structure and shape were found in the entire treated groups at ×10,000 magnification.