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Table 2 Subcutaneous xenograft tumor volumes (cm 3 ) in nude mice

From: In vivo and in vitro evaluation of the cytotoxic effects of Photosan-loaded hollow silica nanoparticles on liver cancer

  Group A Group B Group C P(A/B) P(A/C) P(B/C)
1. 15 15 15 - - -
2. 0.525 ± 0.019 0.520 ± 0.013 0.527 ± 0.015 0.588 0.876 0.487
3. 0.867 ± 0.031 0.250 ± 0.010* 0.412 ± 0.013* 0.000 0.000 0.856
4. 1.236 ± 0.039 0.112 ± 0.013* 0.217 ± 0.011* 0.000 0.000 0.770
5. 1.750 ± 0.169 0.035 ± 0.014*# 0.105 ± 0.038* 0.000 0.000 0.020
6. 2.251 ± 0.162 0.114 ± 0.020*# 0.406 ± 0.050* 0.000 0.000 0.001
7. 2.451 ± 0.397 0.266 ± 0.042*# 0.608 ± 0.076* 0.000 0.000 0.008
8. 2.657 ± 0.411 0.475 ± 0.058*# 1.058 ± 0.170* 0.000 0.000 0.004
9. 3.050 ± 0.438 0.623 ± 0.108*# 1.551 ± 0.180* 0.000 0.000 0.000
  1. 1. Number of animals; 2. Before treatment; 3. 2 days after treatment; 4. 4 days after treatment; 5. 6 days after treatment; 6. 8 days after treatment; 7. 10 days after treatment; 8. 12 days after treatment; 9. 14 days after treatment; Group A - blank control; Group B - nanoscale Photosan group; Group C - conventional Photosan group; P(A/B) - P value for comparing group A and group B; P(A/C) - P value for comparing group A and group C; P(B/C) - P value for comparing group B and group C. *Significantly different (P < 0.05) from group A, #Significantly different (P < 0.05) from group C.