Table 1 Components, physicochemical properties, and KLH content of various NPs
Group | Components of NPs (mg) | Size (dm. nm) | Polydispersity | Zeta potential (mV) | KLH content (%) | ||||
---|---|---|---|---|---|---|---|---|---|
PLGA | KLH | DOTAP | DOPC | DSPE-PEG | |||||
PK | 200 | 3 | 0 | 0 | 0 | 191.0 ± 15.3 | 0.199 ± 0.012 | -9.7 ± 1.1 | 1.12 ± 0.21 |
LPK ++ | 200 | 3 | 16 | 0 | 4 | 213 ± 38.7 | 0.231 ± 0.022 | 13.9 ± 1.3 | 1.11 ± 0.22 |
LPK - | 200 | 3 | 2 | 14 | 4 | 232.4 ± 34.5 | 0.248 ± 0.018 | -3.6 ± 1.4 | 1.05 ± 0.10 |
LPK + | 200 | 3 | 14 | 2 | 4 | 222.6 ± 21.0 | 0.240 ± 0.019 | 6.4 ± 1.1 | 0.92 ± 0.15 |
LPK -- | 200 | 3 | 0 | 16 | 4 | 208.0 ± 12.0 | 0.219 ± 0.023 | -5.5 ± 0.9 | 0.84 ± 0.03 |