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Table 1 Components, physicochemical properties, and KLH content of various NPs

From: In vitro performance of lipid-PLGA hybrid nanoparticles as an antigen delivery system: lipid composition matters

Group

Components of NPs (mg)

Size (dm. nm)

Polydispersity

Zeta potential (mV)

KLH content (%)

 

PLGA

KLH

DOTAP

DOPC

DSPE-PEG

 

PK

200

3

0

0

0

191.0 ± 15.3

0.199 ± 0.012

-9.7 ± 1.1

1.12 ± 0.21

LPK ++

200

3

16

0

4

213 ± 38.7

0.231 ± 0.022

13.9 ± 1.3

1.11 ± 0.22

LPK -

200

3

2

14

4

232.4 ± 34.5

0.248 ± 0.018

-3.6 ± 1.4

1.05 ± 0.10

LPK +

200

3

14

2

4

222.6 ± 21.0

0.240 ± 0.019

6.4 ± 1.1

0.92 ± 0.15

LPK --

200

3

0

16

4

208.0 ± 12.0

0.219 ± 0.023

-5.5 ± 0.9

0.84 ± 0.03

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