Figure 7
Effects of MNPs@Gly on macrophages. (A) Effects of the nanoparticles on cell morphology of THP-1-derived macrophages exposed to the nanoparticles at different concentrations for 24 and 48 h. (B) Cell apoptosis or necrosis was determined by AO and EB double staining assay. (C) Cell viability was determined by WST-8 assay; the cells were treated with the nanoparticles for 48 h (**P < 0.01, ***P < 0.001 vs normal, n = 3). (D) Cell necrosis was determined by detecting the release of LDH from THP-1-derived macrophages (the cell density was 40,000/cm2, n = 3).