Table 2 Characterization of paclitaxel-incorporated nanoparticles of PHO/PEG block copolymer
Polymer/drug (mg/mg) | Drug contents (%, w/ w) | Particle size (weight average, nm) | ||
---|---|---|---|---|
Theoretical | Experimental | |||
PHO | 45/5 | 10 | 7.1 | 115.1 |
PHO/PEG 2 K | 45/5 | 10 | 6.8 | 103.1 |
PHO/PEG 5 K-1 | 45/5 | 10 | 6.5 | 97.6 |
PHO/PEG 5 K-2 | 40/10 | 20 | 11.9 | 110.8 |
PHO/PEG 12 K | 45/5 | 10 | 6.6 | 82.6 |