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Figure 8 | Nanoscale Research Letters

Figure 8

From: Single-step assembly of polymer-lipid hybrid nanoparticles for mitomycin C delivery

Figure 8

In vivo fluorescence imaging and in vivo anticancer effect of the hybrid PLA NPs/MMC-SPC. (A) In vivo fluorescence imaging of H22 tumor-bearing mice after intravenous injection of the DiR-PLA NPs/MMC-SPC at 1, 3, and 12 h post-injection. (B) Ex vivo fluorescence imaging of H22 tumor-bearing mice after intravenous injection of the DiR-PLA NPs/MMC-SPC at 12 h post-injection (Li, liver; S, spleen; K, kidney; H, heart; Lu, lung; T, tumor). (C) The change of tumor volumes of H22 tumor-bearing mice treated with PBS, PLA NPs/SPC, PLA NPs/MMC-SPC, and MMC. (D) The change of body weights of H22 tumor-bearing mice treated with 0.9% NaCl, PLA NPs/SPC, PLA NPs/MMC-SPC, and MMC.

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