Figure 2
From: Enhanced anticancer activity of DM1-loaded star-shaped folate-core PLA-TPGS nanoparticles
In vitro drug release of FA-DM1-NPs. A rapid release was observed from 0 to 5 days, with a cumulative release percentage of 39.2% (linear FA-PLA-TPGS nanoparticles) and 53.4% (star FA-PLA-TPGS nanoparticles) in the first 5 days. Smooth slow release occurred between days 5 and 12, with a cumulative release percentage of 65.5% (star FA-PLA-TPGS nanoparticles) and 44.3% (linear FA-PLA-TPGS nanoparticles). During days 12 to 16, the release reached a plateau, with a cumulative release percentage of 70.7% at day 14.