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Figure 6 | Nanoscale Research Letters

Figure 6

From: Enhanced anticancer activity of DM1-loaded star-shaped folate-core PLA-TPGS nanoparticles

Figure 6

Effect of FA-DM1-NPs and S-DM1 on expression levels of apoptosis-related proteins in MCF-7/HER2 cells. Following the treatment of breast cancer cells with therapeutic concentrations of drugs (5.2 µg/mL S-DM1 and 10 µg/mL FA-DM1-NPs equivalent DM1 5.0 µg/mL, respectively), the expression levels of procaspase-3/-8/-9 and Bcl-2 were analyzed by Western blot (A) and Gel-Pro Analyzer 4.0 software (B). **p <0.01, *p <0.05 vs. control. Results were representative of three independent experiments. Δp <0.05 vs. S-DM1 treatment group.

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