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Figure 1 | Nanoscale Research Letters

Figure 1

From: Size- and time-dependent alteration in metabolic activities of human hepatic cytochrome P450 isozymes by gold nanoparticles via microsomal coincubations

Figure 1

The variation of AuNP-induced inhibition of six CYP450-selective activities at four different particle sizes. The variation of AuNP-induced inhibition of six CYP450-selective activities at four different particle sizes with two microsomal protein concentrations. The monooxygenase activity was expressed as a percentage relative to the activity in the absence of AuNPs. Data points are mean values ± SD derived from duplicate incubations. IC50 were calculated with GraphPad Prism 5.

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