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Table 1 Characterization of FAPuLG copolymer

From: Folic-acid-conjugated pullulan/poly(DL-lactide-co-glycolide) graft copolymer nanoparticles for folate-receptor-mediated drug delivery

Polymer

Theoretical ratio a

  

Experimental ratio c

FA

PU a

PLGA

M.W.

 

FA

PU

PLGA

Pullulan

-

100

-

67,500*

  

100

 

FAPu 1

10

100

-

86,244b

570 mg

9.88

100

 

FAPu 2

20

100

-

105,411b

630 mg

35.8

100

 

PLGA

-

-

100

8,200*

    

PuLG

-

100

1.2

108,684b

250 mg

0

100

1.27

106,696c

FAPuLG 1

10

100

1.2

146,267b

260 mg

6.00

100

1.46

151,453c

FAPuLG 2

20

100

1.2

127,244b

210 mg

21.5

100

1.78

139,918c

  1. *M.W. was evaluated from M.W. of pullulan and PLGA as reported previously [17]. aThe feeding molar ratio of FA and PLGA versus 100 glucose unit of PU; bMn - theoretical value; cMn was analyzed with NMR.

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