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Nanoscale Research Letters
Figure 14 | Nanoscale Research Letters

Figure 14

From: Multidimensional effects of biologically synthesized silver nanoparticles in Helicobacter pylori, Helicobacter felis, and human lung (L132) and lung carcinoma A549 cells

Figure 14

AgNPs modulate mitochondrial transmembrane potential. Changes in mitochondrial transmembrane potential (MTP) was determined using the cationic fluorescent indicator, JC-1. Fluorescence images of control A549 cells and L132 cells (without silver nanoparticles (AgNPs)) and cells treated with AgNPs (30 μg/ml).The changes of mitochondrial membrane potential by AgNPs were obtained using fluorescence microscopy. JC-1 formed red-fluorescent J-aggregates in healthy A549 cells with high MTP, whereas A549 cells exposed to AgNPs had low MTP and, JC-1 existed as a monomer, showing green fluorescence. L132 cells exposed to AgNPs shows healthy and had high MTP.

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