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Figure 1 | Nanoscale Research Letters

Figure 1

From: Selective aggregation of PAMAM dendrimer nanocarriers and PAMAM/ZnPc nanodrugs on human atheromatous carotid tissues: a photodynamic therapy for atherosclerosis

Figure 1

Simplified schematic lay-out of PDT in atherosclerosis. The lipid core plaque (LC) is responsible for stenosis of the aorta (AO). Photons (hv) guided by a fibber (F) illuminate the microphage cells in the plaque (LLM), inducing necrosis following nanoparticle (NP) uptake. SI, side illumination of atheromatous plaque; I, intima; SMC, smooth muscle cells; M, media; A, adventida; FC, foam cell; BF, blood flow; EC, endothelial cells; LDL, low-density lipoprotein; HDL, high-density lipoprotein.

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