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Fig. 3 | Nanoscale Research Letters

Fig. 3

From: A Biomimic Reconstituted High-Density-Lipoprotein-Based Drug and p53 Gene Co-delivery System for Effective Antiangiogenesis Therapy of Bladder Cancer

Fig. 3

Synergistic therapeutic effect of rHDL/CD-PEI/p53 complexes in suppressing VEGF and AT1R expression in MBT-2 cells. Ang II (100 nM) was utilized to simulate an in vivo tumor microenvironment with high Ang II concentration. PCR assay of the suppression on VEGF (a) and AT1R (b) mRNA levels. c Western blotting assay. d ELISA assay. Results are expressed as mean ± SD (n = 5). *P < 0.05 and **P < 0.01

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