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Fig. 6 | Nanoscale Research Letters

Fig. 6

From: Enhanced Antifungal Activity by Ab-Modified Amphotericin B-Loaded Nanoparticles Using a pH-Responsive Block Copolymer

Fig. 6

Nephrotoxicity assessment after treatment of different AMB formulations. a Blood urea nitrogen (BUN) and plasma creatinine (Cr) in mice. *p < 0.01, vs free AMB; data presented as mean ± SEM. n = 3. b Normal mice showed no abnormality and without KIM-1 or NGAL expression. AMB treatment showed high level of expression of KIM-1 and NGAL, but CDA-AMB-NP treatment revealed very low level of expression of KIM-1 and NGAL

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