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Nanoscale Research Letters

Table 2 Effect of free AMB and AMB-loaded NPs against C. albicans

From: Enhanced Antifungal Activity by Ab-Modified Amphotericin B-Loaded Nanoparticles Using a pH-Responsive Block Copolymer

  MIC (μg/mL, pH = 7.35) MIC (μg/mL, pH = 6.8)
Free AMB 1.0 ± 0.1 1.0 ± 0.2
AMB-NPs 10.0 ± 0.2 11.0 ± 0.2
CDA-AMB-NPs 11.0 ± 0.2 11.0 ± 0.2
  1. Abbreviations: AMB amphotericin B, MIC minimum inhibitory concentration, AMB-NPs 1.0 μg/mL equivalent free AMB 0.1 μg/mL, CDA-AMB-NPs 1.2 μg/mL equivalent free AMB 0.1 μg/mL
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