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Fig. 4 | Nanoscale Research Letters

Fig. 4

From: Smart Nanoparticles Based on Hyaluronic Acid for Redox-Responsive and CD44 Receptor-Mediated Targeting of Tumor

Fig. 4

a Fluorescence images of MDA-MB231 cells. MDA-MB231 cells were exposed to DOX-incorporated HAssLG nanoparticles (DOX concentration, 5 μg/ml) for 1 h. Fluorescence images of cells were observed with CLSM. The CD44 receptor of MDA-MB231 cells was blocked with free HA (0.5 mg/ml) 1 h before treatment of DOX-incorporated nanoparticles. GSH (10mM) was added to study the effect of redox-responsive delivery of nanoparticles. b Flow cytometry analysis of MDA-MB231 cells

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