Fig. 10

Carbon nanoparticles’ fate in vivo after intraperitoneal injection. CNP aggregates were observed in the proximity of the injection site in the stomach serous membrane and localized among the mesentery. The mesentery blood circulation system governed carbon nanoparticle trafficking and systemic translocation. The superior mesenteric vein and the splenic vein come together to form the hepatic portal vein and transport CNP to the liver and spleen, which are mononuclear phagocyte system (MPS) organs. This uptake mechanism involves macrophages in snatching up CNP from blood vessels