Advertisement
Table 1 Size of FLT3 inhibitor conjugated GNP measured by DLS and PdI, their zeta potential together with zeta deviation, LSPR position, and calculated drug loading efficiency
| Sample | Zeta potential (mV) | Zeta deviation (mV) | Diameter (nm) | Polydispersity index (PdI) | LSPR position (nm) | Loading efficiency (%) |
|---|---|---|---|---|---|---|
| GNP | −44 ± 2 | 5 ± 1 | 17 ± 2 | 0.45 | 519 | – |
| GNP-PL | −25 ± 2 | 10 ± 1 | 30 ± 1 | 0.54 | 520 | – |
| GNP-MDS-PL | −20 ± 1 | 9.8 ± 1 | 58 ± 2 | 0.46 | 529 | 80 |
| GNP-SRF-PL | −17.5 ± 0 .5 | 7.8 ± 3 | 48 ± 1 | 0.52 | 526 | 10 |
| GNP-QZR-PL | −5 ± 0.7 | 4 ± 0.2 | 58 ± 2 | 0.53 | 523 | 8 |
| GNP-LST-PL | −10 ± 0.5 | 8.5 ± 0.3 | 44 ± 2 | 0.95 | 527 | 10 |
