Skip to main content
Account

Table 2 Acute toxicity tests in mice by intraperitoneal injection (n = 8)

From: Encapsulation of Aconitine in Self-Assembled Licorice Protein Nanoparticles Reduces the Toxicity In Vivo

Group

Dead

Time to death (min)

Toxic effects

a

0

Normal

b

8

100 ± 15

Gather, eyes close, tremble, convulsions, opisthotonos position

c

0

Gather, eyes close, less active, returned to normal in 3 h

1

0

Normal

2

8

18 ± 5

Gather, eyes close, tremble, convulsions, opisthotonos position

3

8

30 ± 5

Gather, eyes close, tremble, convulsions, opisthotonos position

4

8

50 ± 5

Gather, eyes close, tremble, convulsions, opisthotonos position

5

0

Gather, eyes close, less active, returned to normal in 3 h

Navigation