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Fig. 8 | Nanoscale Research Letters

Fig. 8

From: Effect of Terminal Groups of Dendrimers in the Complexation with Antisense Oligonucleotides and Cell Uptake

Fig. 8

PAMAM-NH2/asODN but not PAMAM-OH/asODN complexes bind to the cell membrane. Cells were grown on coverslips, and after 70 % confluence, cells were incubated with a PAMAM-NH2/asODN (charge ratio 1:1) and b PAMAM-OH/asODN (equivalent in weight to 1:1 PAMAM-NH2/asODN 1:1 charge ratio). Time-lapse image sequence was performed using a TIRF microscope. Arrows indicate complexes that after some seconds disappear

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